Why is Vitamin D so important?

Early science understood the calcium homeostasis role of Vitamin D and bone health. However, we now know that vitamin D plays a major biological role in human physiology, cell differentiation, proliferation (1) and immunity. In our new understanding, we realise it is no longer recommended to have merely sufficient levels of Vitamin D to avoid rickets. […]
How is Vitamin D made?

In the presence of UVB rays from the sun, a precursor, pre-vitamin D is made in the epidermis from a derivative of cholesterol in the skin. This is then made into D3 in the lower layers of the skin. (cholecalciferol) The liver converts this to calcidiol (25-hydroxy vitamin D), and another conversion to calcitriol 1,25 […]